Almost every pharmaceuticals vennoe substance is in pharmacies in different forms Which are used for different indications. Today there are more than 50 kinds of dosage forms, they vary not only and not so much the appearance of many ways to manufacture, use, and has an effect.
For example, a drug in an injection is delivered directly into the blood and is faster, it is important in the treatment of serious inflammatory processes, to enhance the effect of antibiotics in relieving postoperative pain. Tablet forms are not immediately they must pass through the digestive tract, where there is a splitting and swelling of the tablets, which then dissolve the active substance passes into the liquid form, is evacuated from the stomach and is absorbed in the small intestine. Drops and syrups bypassed the step of swelling and dissolution, they just pass through the stomach into the intestine and begin to act faster tablets.
The drugs are constantly being improved, are nothing new tablets with prolonged (extended) effect. But the pills have the property "float" in the gastric juice, they appeared relatively recently and have gained much popularity because they reduce the acidity of gastric juice over a longer period. Tablet form drugs vnedarom popular - with their help it is easy to adjust the dosage, they are stored for a long time, but most importantly - cheap cost manufacturer, which allows to keep the prices for drugs in tablet form rather low.
Capsules - a special form of drugs, which are made from substances that are readily soluble in the stomach. Accordingly, the active ingredient is released more rapidly and it is not necessary to inflate as a tablet, as medicine capsules often it stored in powder form and immediately begins to dissolve.
At capsules compared to tablets many advantages - they are easy to swallow, they do not irritate the mucous membrane of the stomach, they do not have an unpleasant odor and taste. In addition, it is capsulated form allows you to control the release of the drug, increasing its effectiveness, they are made from natural ingredients and allow to reduce the number of inactive accompanying substances. While this dosage form drugs is not as widespread in Russia - only 30% of oral drugs are available in capsules.
New promising development, which will soon appear on the Russian market, cellulose capsules or, more precisely, the capsule of plant origin and hypromellose Vcaps Vcaps Plus. Notify the company recently Capsugel, specializing in the production of innovative dosage forms. These capsules are not a part of gelling agents or further auxiliaries, which excludes the possibility of an allergic reaction, they are consistently resistant to changes in the external environment (ie, an increase in temperature and humidity). Dissolve in the stomach and intestines irrespective of pH, provide reliable delivery of active ingredients.
Now more and more widely used in medicine are so-called "complex compositions" drugs, ie, various forms of medications that enter into the capsule shell. Typically, they are sensitive to moisture and it is therefore preferred cellulose capsules which consist of a material with low moisture content: 5-6% (at the level of the ambient relative humidity 50%). Moreover, these capsules do not retain moisture in high humidity conditions and can be used for the production of drugs, which should not contain gelatine. By the way, the lack of vegetarian gelatine capsules - another plus.
Oksana Herasymenko
Treatment and prevention
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