American oncologists from the Center for Cancer Memorial Sloan-Kettering offer to fight this deadly disease by gene therapy. The scientists have already tested its effectiveness on sick people. Two people suffering from acute lymphoblastic leukemia, recovered 2 months, another - in just 8 days.
In fairness it should be noted that in the experiment the scientists involved five people. Two of them later died, one as a result of vascular occlusion (that death is not related to therapy), the other - after exacerbation. Even so, the development of indicators of American scientists - a major breakthrough in the treatment of acute leukemia As conventional therapy assists only 30 - 60%.
In the journal Science Translational Medicine, researchers explained in detail the essence of the developed treatments. They first identified in patients T lymphocytes and "programmed" them to look for cancer cells. Since the molecules have been found (B white blood cells) which contain a unique protein CD19, which is responsible for the development of the disease. Thereafter own T cells attack and destroy the patient's infected cells synthesize the harmful protein.
Currently, all three American scientists patient is in remission. To restore their immune system of the patient a bone marrow transplant. Researchers estimate that to restore the normal balance of T-lymphocytes and B-lymphocytes healthy in their blood will take several months, and the process of full recovery will take from five months to two years.
In the near future, oncologists will conduct a similar experiment with the participation of 50 people suffering from acute lymphoblastic leukemia, and then will evaluate the effectiveness of gene therapy for patients with other forms of cancer. (READ MORE)
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